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Kidney, "" pre, post or kidney?



We understand that it is a chronic and acute renal failure. We realize the importance of good blood test for diagnosis. And increasingly clear that we also have to look a complete blood analysis, blood pressure measurement and ultrasound. Unable to reach a good resolution of the case without properly testing.

One of the first problems that we can find, before performing other tests, when we performed the blood tests and see the BUN (blood urea nitrogen) and creatinine increased, it is. What type of kidney failure I have before?.

Often the clinical signs can have an idea ... clogged cat with a high bun and creatinine has all the ballots for a postrenal IRC. A dog cardiopathy with a shortening fraction and stroke volume decreased has much to be pre-renal failure.

However we can not diagnose random, we have testing. Although initially there is a simple way to get more data on whether or renal failure is prerenal ... Is the calculation of the ratio urea / CREA. This calculation is performed with the values \u200b\u200bwe already have thanks to that first test, and only requires following a simple process of development and have a calculator hand.

Let's see how is done and what they mean:

First we know that the formula we have to do is simple ... we will make a division between ..


UREA (mmol / l) / creatinine (micromol / l ).....


The first problem that we often find is that the values \u200b\u200bthat gives us analytical machine is not in mmol or micromoles ... but you can make conversions simply following the following rules. Skip

creatinine md / dl micromol / l ..... multiply by 88.4

Skip BUN (mg / dl) to urea (mmol / l) multiplied by 0.36


therefore once we have passed BUN for urea (unless our analyzer and us than UREA mmol / l can also be), and creatinine to micromoles per liter, divide these values \u200b\u200band we will get a result.

If the value is greater than 0.08 ... clearly indicate that we are prerenal azotemia, the same way that even a urine specific gravity (in urine by refractometer) over 1025 (1030).

If a value of RATIO (UREA / CREA) is equal to or less than 0.08 indicates that there is a renal azotemia, as well as indicate a low urine specific gravity (from around 1012, when there are 3 / 4 altered parts of the nephrons).

And knowing that our diagnosis differential would be much more successful, and therefore to perform diagnostic tests may also be different.



Alexis J. Santana González. DVM. Col 829